Manager, Bioinformatics Operations - Immunology

The mission of the Allen Institute is to unlock the complexities of bioscience and advance our knowledge to improve human health. Using an open science, multi-scale, team-oriented approach, the Allen Institute focuses on accelerating foundational research, developing standards and models, and cultivating new ideas to make a broad, transformational impact on science.

The mission of the Allen Institute for Immunology is to advance the fundamental understanding of human immunology through the study of immune health and diseases where excessive or impaired immune responses drive pathological processes. The Institute will employ a multi-disciplinary team approach in collaboration with academic centers of human immunology to generate novel mechanistic insights into the immune synapse in health and in diseases such as autoimmunity or oncology. The Institute will simultaneously provide a foundational data set and tools for future immunological research as well as a novel collaboration portal for the broader scientific community.

The Allen Institute for Immunology is seeking a Manager of Bioinformatics Operations with broad experience in analyzing and developing analysis tools for single-cell omics data to manage day-to-day bioinformatics operations. Reporting to the Director of Informatics & Computational Biology at the Allen Institute for Immunology, the ideal candidate is a self-motivated team player who can work closely with immunologists, bioinformaticians, and software developers. The ideal candidate is an excellent communicator who can translate ideas into solid data analysis plans and testable hypotheses, an experienced tool developer who can standardize internal and external analysis scripts, a good organizer who can manage multiple projects simultaneously, a quick learner who can adapt new methodologies to achieve goals, and a tireless worker who can complete projects under time constraints. The successful candidate will mentor and manage a small group of Bioinformatics Analysts.

The Allen Institute believes that team science significantly benefits from the participation of diverse voices, experiences and backgrounds. High-quality science can only be produced when it includes different perspectives. We are committed to increasing diversity across every team and encourage people from all backgrounds to apply for this role.

Essential Functions

• Perform and/or supervise analysis of clinical metadata and multi-modal omics data, including but not limited to: scRNA-seq, scATAC-seq, CITE-seq, TEA-seq, flow cytometry, and proteomics
• Lead continuous standardization and improvement on our data analysis pipelines, including both internal and external software tools
• Develop data analysis plans and execute the plans for hypothesis generation
• Review, implement, troubleshoot, and improve analytic methods developed by others internally or externally
• Develop and/or implement new analysis pipelines with cross-functional teams
• Meet production deadlines for data analysis and be able to pivot between multiple projects
• Manage a small group of Bioinformatics Analysts

Note: Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. This description reflects management’s assignment of essential functions; it does not proscribe or restrict the tasks that may be assigned.

Required Education and Experience

• Bachelor’s degree in a scientific field
• 6 years of equivalent experience
• Broad experience in analyzing diverse types of data, including clinical metadata and high throughput omics data
• Demonstrated experience in developing tools for omics data analysis
• Experience in leading bioinformatics projects
• Track record of working with cross-functional teams
• General understanding of molecular biology and wet-lab omics technologies
• Fluency in R and/or Python

Preferred Education and Experience

• Master’s or PhD in bioinformatics or closely related disciplines, with a minimum of 3 years of equivalent experience
• 6-10 years of experience in biological and/or medical research
• Basic knowledge of human immunology
• Familiarity with cloud computing and/or Linux
• Experience using Git or similar version control system
• Excellent organizational, teamwork, presentational and communication skills
• Good judgment and problem-solving skills, curious, and eager to take new challenges
• Demonstrated success in a multidisciplinary team environment
• Experience in mentoring and/or managing junior colleagues
• Self-motivated, a team player, attentive to details, and able to handle multiple projects simultaneously under time constraints

Work Environment

• May enter laboratory environment - possible exposure to chemical, biological, or other hazardous substances

Physical Demands

• Fine motor movements in fingers/hands to operate computers and other office equipment; repetitive motion with lab equipment

Position Type/Expected Hours of Work

• Occasional evening and weekend hours required
• This role is currently able to work both remotely and onsite in a hybrid work environment. We are a Washington State employer, and the primary work location for all Allen Institute employees is 615 Westlake Ave N.; any remote work must be performed in Washington State.

Travel

• Attendance and participation in national and international conferences may be required

Additional Comments

• **Please note, this opportunity offers relocation assistance**
• **Please note, this opportunity offers work visa sponsorship**

Annualized Salary Range

• $124,050 - $165,400 *

* Final salary depends on required education for the role, experience, and level of skills relevant to the role, along with work location, where applicable.

Benefits

• Employees (and their families) are eligible to enroll in benefits per eligibility rules outlined in the Allen Institute’s Benefits Guide. These benefits include medical, dental, vision, and basic life insurance. Employees are also eligible to enroll in the Allen Institute’s 401k plan. Paid time off is also available as outlined in the Allen Institute's Benefits Guide. Details on the Allen Institute’s benefits offering are located at the following link to the Benefits Guide: https://alleninstitute.org/careers/benefits.

It is the policy of the Allen Institute to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by federal, state, or local law. In addition, the Allen Institute will provide reasonable accommodations for qualified individuals with disabilities.