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Research Associate I – Tissue Processing

Department: Electrophysiology

Research Associate I – Tissue Processing

The mission of the Allen Institute is to unlock the complexities of bioscience and advance our knowledge to improve human health. Using an open science, multi-scale, team-oriented approach, the Allen Institute focuses on accelerating foundational research, developing standards and models, and cultivating new ideas to make a broad, transformational impact on science.

The mission of the Allen Institute for Brain Science is to accelerate the understanding of how the human brain works in health and disease. Using a big science approach, we generate useful public resources, drive technological and analytical advances, and discover fundamental brain properties through integration of experiments, modeling and theory.

This Research Associate I will support projects aimed to classify cell types within the brain and be responsible for executing a variety of laboratory tasks and/or experiments in a high-throughput laboratory and animal care environment following Standard Operating Procedures (SOPs). Good judgment and problem-solving skills are required for recognizing process deviations, participating in troubleshooting, and operation of complex laboratory instrumentation.

This role is expected to comply with regulatory requirements, adhere to SOPs, initiate individual experiments and to work efficiently in a team environment.

The Allen Institute believes that team science significantly benefits from the participation of diverse voices, experiences and backgrounds. High-quality science can only be produced when it includes different perspectives. We are committed to increasing diversity across every team and encourage people from all backgrounds to apply for this role.

Essential Functions

  • Performance of acute surgical procedures and tissue dissections
  • Handling of mice
  • Processing mouse, human, and non-human primate brain tissue
  • Dissociation and preparation of single cell/nuclei samples for analysis
  • Cell and tissue histological staining
  • Follow SOPs, good laboratory practices, and regulatory requirements
  • Maintain accurate laboratory documentation and reporting using established methods
  • Work with supervisor to appropriately manage time and prioritize tasks

Note: Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. This description reflects management’s assignment of essential functions; it does not proscribe or restrict the tasks that may be assigned.

Required Education and Experience

  • Bachelor’s degree in a life science or related field

Preferred Education and Experience

  • 1+ years of related work experience and/or training preferred
  • Exceptional manual dexterity and attention to detail
  • Basic knowledge of mouse neuroanatomy, genetics, flow cytometry, RNA sequencing, electrophysiology and/or cell biology
  • Experience working with mice and/or tissue samples
  • Experience with fluorescence and/or dissection microscopy
  • Ability to critically interpret and analyze scientific data
  • Intermediate level ability with Microsoft Office suite and the ability to learn other custom software systems
  • Ability to work independently and as a part of a collaborative team

Work Environment

  • Work requires proper use of personal protective equipment and engineering controls
  • Laboratory duties involve safely handling or working near chemical, biological or other hazardous substances

Animal Care Services

  • Exposure to and handling of laboratory animals required
  • Perform euthanasia, surgical procedures, and tissue collections

Physical Demands

  • Occasional lifting up to 30 pounds
  • Fine motor movements in fingers/hands to operate computers and other office and lab equipment; repetitive motion with lab equipment
  • Push/pull a cart
  • Stooping, bending, crouching, sitting

Position Type/Expected Hours of Work

  • This is an essential job and expected to report for work regardless of weather and/or other conditions
  • Rotating evening on-call coverage
  • Occasional evening hours required
  • This role is currently working onsite and is expected to work onsite for the majority of working hours. The primary work location for this role is 615 Westlake Ave N., with flexibility to work remotely on a limited basis.

Additional Eligibility Qualifications

  • In keeping with our focus on employee safety, all employees must be up to date with vaccinations against COVID-19 as a condition of employment unless a medical or religious accommodation is approved. All employees will be required to keep their vaccination status up to date according to CDC guidance.

It is the policy of the Allen Institute to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by federal, state or local law. In addition, the Allen Institute will provide reasonable accommodations for qualified individuals with disabilities.





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