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Research Associate I – Molecular Anatomy

Department: Neural Dynamics - Molecular Anatomy

Research Associate I – Molecular Anatomy

The mission of the Allen Institute is to unlock the complexities of bioscience and advance our knowledge to improve human health. Using an open science, multi-scale, team-oriented approach, the Allen Institute focuses on accelerating foundational research, developing standards and models, and cultivating new ideas to make a broad, transformational impact on science.

The mission of the Allen Institute for Neural Dynamics is focused on fundamental discoveries in systems neuroscience. We are interested in how the brain builds our understanding of the complex world to guide the flexible behaviors that address our biological needs. The answers will be in terms of defined neuron types and circuits interacting across the whole brain and body. We will develop next-generation methods and theories and employ a team-based approach for discovery neuroscience. Knowledge, data, models, and tools will be widely shared, in part to support the development of therapies for brain disorders. Knowledge, data, and tools will be widely shared, in part to support the development of therapies for brain disorders.

As part of this initiative, we plan to generate high-value data sets, mapping brain-wide connectivity of neurons at multiple scales and with molecular specificity. We are seeking a Research Assistant with a background in neuroscience or related biological sciences to support ongoing research projects investigating large-scale circuitry of the brain. Experimental approaches include tissue-sectioning, tissue clearing and tissue expansion, RNA and protein localization in tissue sections and intact brains, and microscopy. We seek an individual who will take responsibility for key tasks and work closely with other team members to achieve the team's goals. The successful applicant will receive training in all relevant techniques, but prior experience in related histological techniques would be beneficial.

The Allen Institute believes that team science significantly benefits from the participation of diverse voices, experiences and backgrounds. High-quality science can only be produced when it includes different perspectives. We are committed to increasing diversity across every team and encourage people from all backgrounds to apply for this role.

Essential Functions

  • Professional handling of fixed and unfixed biological specimens
  • Tissue fixation techniques and tissue clearing
  • Experience with thin sectioning techniques using microtomes and cryostats
  • Experience with fluorescent in situ hybridization methods
  • Immunocytochemistry, immunohistochemistry, histology, and related tissue staining techniques
  • Light and confocal microscopy, image viewing in Fiji or Photoshop
  • Data tracking and organization via lab notebooks and spreadsheets
  • Support PhD-level scientists by assisting with their projects and large internal team science efforts
  • Communicate effectively with others inside and outside the organization, e.g. through presentations within the institute and at scientific conferences, and publications in peer-reviewed journals

Note: Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. This description reflects management’s assignment of essential functions; it does not proscribe or restrict the tasks that may be assigned.

Required Education and Experience

  • Bachelor’s degree in Neuroscience, Physiology or related field
  • Demonstrated problem-solving and experiment management skills
  • Proven ability to meet aggressive timelines and deliverables

Preferred Education and Experience

  • Experience with biological microscopy, tissue expansion and super resolution techniques
  • Strong written and verbal communication skills
  • Ability to work in a high-performance group environment

Work Environment

  • May enter laboratory environment, including potential exposure to lasers, biohazards

Animal Care Services

  • May require exposure to and handling of laboratory animals, including pre- and post-operative care for mice
  • May require performing euthanasia and tissue collections from mice

Physical Demands

  • Occasional lifting to 30 pounds
  • Fine motor movements in fingers/hands to operate computers and other office equipment, lab equipment

Position Type/Expected Hours of Work

  • This role is currently working onsite and is expected to work onsite for the majority of working hours. The primary work location for this role is 615 Westlake Ave N., with flexibility to work remotely on a limited basis.

Additional Eligibility Qualifications

  • In keeping with our focus on employee safety, all employees must be up to date with vaccinations against COVID-19 as a condition of employment unless a medical or religious accommodation is approved. All employees will be required to keep their vaccination status up to date according to CDC guidance.

It is the policy of the Allen Institute to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by federal, state or local law. In addition, the Allen Institute will provide reasonable accommodations for qualified individuals with disabilities.





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