Scientist II – Neuroimmune Proteomics

The mission of the Allen Institute is to unlock the complexities of bioscience and advance our knowledge to improve human health. Using an open science, multi-scale, team-oriented approach, the Allen Institute focuses on accelerating foundational research, developing standards and models, and cultivating new ideas to make a broad, transformational impact on science.

The mission of the Allen Institute for Immunology is to advance the fundamental understanding of human immunology through the study of immune health and diseases where excessive or impaired immune responses drive pathological processes. The Institute will employ a multi-disciplinary team approach in collaboration with academic centers of human immunology to generate novel mechanistic insights into the immune synapse in health and in diseases such as autoimmunity or oncology. The Institute will simultaneously provide a foundational data set and tools for future immunological research as well as a novel collaboration portal for the broader scientific community.

The Allen Institute for Immunology is looking for an exceptional molecular immunologist (Scientist II) to join a team focused on using and developing proteomic approaches to comprehensively study the interactions of the nervous system and the immune system in the setting of viral infection, cancer and autoimmune diseases. Specific responsibilities will include analysis and synthesis of data generated through our cellular, molecular and proteomic platforms, design and development of new assays, and in vitro and ex vivo immunologic studies partially in the context of viral infections (LCMV) to test existing and new hypotheses. The ability to function in a team to bring projects to completion on a timeline is essential.

The successful candidate will have a strong background in proteomic methodologies and neuroscience and/or immunology. Strongest consideration will be given to candidates with a proven track record in identifying and progressing novel hypotheses forward in discovery research and/or translational settings. Direct experience with advanced approaches in proteomic chemistry including mass-spectrometry and proximity labeling is highly desired. This is limited term position expected to last through December 2026.

The Allen Institute believes that team science significantly benefits from the participation of diverse voices, experiences, and backgrounds. High-quality science can only be produced when it includes different perspectives. We are committed to increasing diversity across every team and encourage people from all backgrounds to apply for this role.

Essential Functions

• Support the development and application of proteomic technologies to drive biological insight in the context of neuroimmunology, examples include mass-spectrometry
• Design, execute and analyze in vitro and in vivo immunologic studies and utilization of genetic mouse models to test existing and new hypotheses
• Collaboration with a team to bring projects to completion on a timeline

Note: Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. This description reflects management’s assignment of essential functions; it does not proscribe or restrict the tasks that may be assigned.

Required Education and Experience

• Ph.D. or equivalent combination of degree and experience in a life sciences discipline
• 3+ years of postdoctoral experience

Preferred Education and Experience

• A strong background in proteomic technologies including mass-spectrometry, proximity labeling and protein conjugation chemistry
• Experience in cellular immunology and/or neuroscience
• Direct experience with advanced approaches in deconstructing immunologic mechanisms & testing hypotheses (e.g. targeted mutagenesis using CRISPR/Cas9, phenotypic screening, antibody-based immune modulation, cell culture, etc.)
• Proven success in troubleshooting and innovation on existing platforms, including publications and/or patents
• Demonstrated ability to independently analyze data through coding languages (R, python, bash, version control)
• Exceptional oral and written communication skills and ability to effectively present complicated concepts internally and externally in a cross-discipline environment

Work Environment

• Working in a laboratory environment with potential exposure to lasers, biohazards

Physical Demands

• Occasional lifting to 30 pounds
• Fine motor movements in fingers/hands to operate computers and other office equipment; repetitive motion with lab equipment
• Stooping, bending, crouching

Position Type/Expected Hours of Work

• May need to work outside of standard working hours at times
• This role is currently working onsite and is expected to work onsite for the majority of working hours. The primary work location for this role is 615 Westlake Ave N., with flexibility to work remotely on a limited basis. We are a Washington State employer; any remote work must be performed in Washington State.
• This is a limited term position expected to last through December 2026 based on business needs and funding

Additional Eligibility Qualifications

• All employees who work with live animals must complete an Occupational Health medical history form and/or consultation with an Occupational Health Provider and receive clearance to work with animals. Depending on your health history and job responsibilities, an annual respiratory health screening and clearance to use a respirator may also be required.

Additional Comments

• **Please note, this opportunity does sponsor work visas**
• **Please note, this opportunity does offer relocation assistance**

Annualized Salary Range

• $104,050 - $128,700 *

* Final salary depends on required education for the role, experience, and level of skills relevant to the role, along with work location, where applicable.

Benefits

• Employees (and their families) are eligible to enroll in benefits per eligibility rules outlined in the Allen Institute’s Benefits Guide. These benefits include medical, dental, vision, and basic life insurance. Employees are also eligible to enroll in the Allen Institute’s 401k plan. Paid time off is also available as outlined in the Allen Institute’s Benefits Guide. Details on the Allen Institute’s benefits offering are located at the following link to the Benefits Guide: https://alleninstitute.org/careers/benefits.

It is the policy of the Allen Institute to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by federal, state or local law. In addition, the Allen Institute will provide reasonable accommodations for qualified individuals with disabilities.