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Research Associate I, Stem Cell and Gene Editing

Department: StemCell Gene Editing

Research Associate I, Stem Cell and Gene Editing – Cell Science

The mission of the Allen Institute is to unlock the complexities of bioscience and advance our knowledge to improve human health. Using an open science, multi-scale, team-oriented approach, the Allen Institute focuses on accelerating foundational research, developing standards and models, and cultivating new ideas to make a broad, transformational impact on science.

The mission of the Allen Institute for Cell Science is to create multi-scale visual models of cell organization, dynamics, and activities. Our approach encompasses large scale data collection, observation, theory, and predictions to understand cellular behavior in normal and pathological contexts. As a division within the Allen Institute, the Allen Institute for Cell Science uses a team-oriented approach, focusing on accelerating foundational research, developing standards and models, and cultivating new ideas to make a transformational impact on science.

We are seeking a motivated and team-oriented Research Associate with excellent molecular biology and cell culture skills to join the Stem Cells and Gene Editing team at the Allen Institute for Cell Science. The Research Associate will assist in the gene editing pipeline to support the “Allen Cell Collection” which includes the generation, maintenance, and characterization of gene edited hiPSC lines using CRISPR-Cas9. The resulting highly QCed cell lines will be used for internal projects as well as distribution to the research community worldwide.

The research associate will also help the team with additional research projects involving gene editing, stem cell culture and stem cell differentiation and will help coordinate projects across various internal teams. Exceptional candidates with proven expertise in molecular biology will have opportunities to lead gene editing method development projects as needed. The ideal candidate will have a strong background in cell culture and molecular biology, commitment to collaborative team-based projects, and an interest in developing a range of invaluable tools for cell biology research both within and outside of the institute.

The Allen Institute believes that team science significantly benefits from the participation of diverse voices, experiences and backgrounds. High-quality science can only be produced when it includes different perspectives. We are committed to increasing diversity across every team and encourage people from all backgrounds to apply for this role.

**Please provide a cover letter to be considered for this opportunity**

Essential Functions

  • Employ CRISPR/Cas9-based gene editing methods to generate precisely edited hiPSC lines
  • Routinely perform molecular biology experiments using several PCR based technologies
  • Precisely follow protocols and workflows for gene editing and cell culture
  • Testing and troubleshooting new methods and equipment
  • Maintain meticulous records and organize and maintain libraries of reagents
  • Work closely with other scientists to coordinate complex experiments
  • Adherence to SOPs, GLPs and regulatory requirements
  • Properly handle hazardous chemicals
  • Assist cross-functional activities including hand-offs to various teams, compiling data, and presenting at project meetings
  • Work on a non-conventional schedule, which includes partial days on weekends

Note: Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. This description reflects management’s assignment of essential functions; it does not proscribe or restrict the tasks that may be assigned.

Required Education and Experience

  • Bachelor’s Degree in cell biology, or a related biological life science

Preferred Education and Experience

  • 0 – 2 years of relevant post-undergraduate experience
  • Strong background in cell biology
  • Experience or knowledge of laboratory practices related to human stem cell culture or differentiation
  • Strong interpersonal and organization skills, careful attention to detail, and ability to work both independently and collaboratively

Physical Demands

  • Occasional lifting to 30 pounds
  • Fine motor movements in fingers/hands to operate computers and other office equipment; repetitive motion with lab equipment

Position Type/Expected Hours of Work

  • Please note, this position requires work approximately 4 to 5 hours Saturdays and Sundays, flexible scheduling weekdays every week, and holidays. Regular weekend work is required and will be accommodated with flexible scheduling during the workweek.
  • This role is currently working onsite and remotely when possible, due to COVID-19 and our focus on employee safety. We continue to evaluate the safest options for our employees.

Additional Comments

  • **Please note, this opportunity does not sponsor work visas and has no relocation assistance**


It is the policy of the Allen Institute to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by federal, state or local law. In addition, the Allen Institute will provide reasonable accommodations for qualified individuals with disabilities.





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