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Research Associate II - Molecular Genetics

Department: Molecular Genetics

Research Associate II – Molecular Genetics

 

The mission of the Allen Institute is to unlock the complexities of bioscience and advance our knowledge to improve human health. Using an open science, multi-scale, team-oriented approach, the Allen Institute focuses on accelerating foundational research, developing standards and models, and cultivating new ideas to make a broad, transformational impact on science.

The mission of the Allen Institute for Brain Science is to accelerate the understanding of how the human brain works in health and disease. Using a big science approach, we generate useful public resources, drive technological and analytical advances, and discover fundamental brain properties through integration of experiments, modeling and theory.

We are seeking a Research Associate who will be part of a multidisciplinary team within the Cell Types Program. The successful candidate will be a member of the Molecular Genetics team, which produces and analyzes large-scale single-cell transcriptomics data from primary mouse brain tissue, to define cell types within the brain. The candidate will play a role in creating, processing, and analyzing single-cell transcriptomics and epigenomics data and will make improvements to the experimental and computational pipeline.

The Allen Institute believes that team science significantly benefits from the participation of diverse voices, experiences, and backgrounds. High-quality science can only be produced when it includes different perspectives. We are committed to increasing diversity across every team and encourage people from all backgrounds to apply for this role.

Essential Functions

  • Contribute to experimental method optimization for single-cell genomics
  • Collaborate with bioinformatics scientists to analyze and interpret data
  • Test and optimize algorithms that improve genomics processing and analysis pipelines
  • Prepare sequencing data for sharing with internal and external collaborators

Note: Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. This description reflects management’s assignment of essential functions; it does not proscribe or restrict the tasks that may be assigned.

Required Education and Experience

  • Bachelors degree in life science (e.g., Neuroscience, Molecular Biology, Genetics)
  • Experience with single-cell genomics & experimental methods development
  • Proficiency in Python or R and Linux shell scripting
  • 2 years work experience in a life science-related field

Preferred Education and Experience

  • 2 - 5 years work experience in a life science-related field
  • Familiarity with cloud computing environments
  • Experience with PCR, imaging, cell culture, and nuclei isolation
  • Knowledge about RNA-seq, ATAC-seq, and/or ChIP seq high throughput data analysis
  • Ability to implement, test, and share new computational tools quickly, in an iterative manner, after feedback from experimental, data production, and analysis teams

Work Environment

  • Office environment
  • Laboratory environment, including potential exposure to lasers, biohazards

Physical Demands

  • Fine motor movements in fingers/hands to operate computers and other office equipment, repetitive motion with lab equipment
  • Push/pull up to 5 pounds; occasional lifting to 10 pounds
  • Stooping, bending, crouching, reaching, or climbing ladders

Position Type/Expected Hours of Work

  • 50% work in on-site in laboratory environment and 50% computational remote work from home
  • This role is currently working onsite and remotely, when possible, due to COVID-19 and our focus on employee safety. We continue to evaluate the safest options for our employees.

Additional Comments

  • **Please note, this opportunity does not offer relocation assistance**
  • **Please note, this opportunity does not offer work visa sponsorship**

 

It is the policy of the Allen Institute to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by federal, state or local law. In addition, the Allen Institute will provide reasonable accommodations for qualified individuals with disabilities.

 

 
 
 
 

 

 
 

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