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Scientist II - Neuro-engineer for Neuropixels Brain Observatory- Mindscope

Department: Neural Circuits and Behavior

Scientist II – Neuro-engineer for Neuropixels Brain Observatory

The mission of the Allen Institute is to unlock the complexities of bioscience and advance our knowledge to improve human health. Using an open science, multi-scale, team-oriented approach, the Allen Institute focuses on accelerating foundational research, developing standards and models, and cultivating new ideas to make a broad, transformational impact on science.

The MindScope program seeks to understand the transformations, sometimes called computations, in coding and decoding that lead from photons to behavior and conscious experience by observing, perturbing and modeling the physical transformations of signals in the cortical-thalamic visual system within a few perception-action cycles.

We seek an experienced Scientist who will work as a lead technical Neuro-engineer for our Neuropixels Brain Observatory. Using this observatory we are collecting large-scale, standardized datasets of spiking activity in the mouse brain ( This Neuro-engineer will be a critical member of a multi-functional team that includes experimental scientists, research associates (technicians), and software engineers. We encourage applications from scientists interested in solving hands-on science and engineering problems in a team-based environment.    

The Allen Institute believes that team science significantly benefits from the participation of diverse voices, experiences and backgrounds. High-quality science can only be produced when it includes different perspectives. We are committed to increasing diversity across every team and encourage people from all backgrounds to apply for this role.

Essential Functions

  • Maintain and calibrate Neuropixels rigs and associated hardware devices
  • Empirically test Neuropixels rig performance and track trends over time
  • Install Neuropixels probes on recording rigs and calibrate probe targeting
  • Set up new recording configurations and experimental workflows
  • Work with scientific teams to plan and implement of new experiments
  • Work with mechanical engineering team and outside manufacturers to troubleshoot and upgrade Neuropixels rig
  • Calibrate sensory stimulation hardware and video-based experimental monitoring
  • Set up and calibrate optogenetic stimulation hardware

Note: Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. This description reflects management’s assignment of essential functions; it does not proscribe or restrict the tasks that may be assigned.

Required Education and Experience

  • PhD or equivalent in Neuroscience, Bioengineering, or related discipline; or equivalent combination of degree and experience
  • 3 years of relevant work experience
  • Experience with neurophysiological recordings
  • Experience programming in Python or Matlab

Preferred Education and Experience

  • 5-7 years of work experience with neurophysiological recordings
  • Familiarity with Neuropixels probes and/or other high-density extracellular recording probes
  • Experience working on team-based science and engineering projects
  • Strong computational and data analysis skills related to neurophysiological recordings
  • Track record of scientific excellence and independent thinking
  • Effective verbal and written communication skills

Work Environment

  • Will enter laboratory environment, including potential exposure to lasers, biohazards
  • Handling mice in a laboratory environment

Physical Demands

  • Fine motor movements in fingers/hands to operate computers and other office equipment; repetitive motion with lab equipment
  • Stooping, bending, crouching, reaching, or climbing ladders

Position Type/Expected Hours of Work

  • Occasional evening and weekend hours required  
  • This role is currently working onsite.  Due to COVID-19 and our focus on employee safety we continue to evaluate the safest options for our employees.

Additional Comments

  • **Please note, this opportunity offers relocation assistance**
  • **Please note, this opportunity offers work visa sponsorship**


It is the policy of the Allen Institute to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by federal, state or local law. In addition, the Allen Institute will provide reasonable accommodations for qualified individuals with disabilities.





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