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Sr. Research Associate/Research Associate III – Molecular Genetics: Methods Development, Genomics

Department: 2390 - Molecular Genetics
Location: Seattle

Sr. Research Associate/Research Associate III – Molecular Genetics: Methods Development, Genomics 

The mission of the Allen Institute is to uncover the complexities of bioscience and advance our knowledge to improve human health. Using an open science, multi-scale, team-oriented approach, the Allen Institute focuses on accelerating foundational research, developing standards and models, and cultivating new ideas to make a broad, transformational impact on science.

The Allen Institute believes that team science significantly benefits from the participation of diverse voices, experiences and backgrounds. High-quality science can only be produced when it includes different perspectives. We are committed to increasing diversity across every team and encourage people from all backgrounds to apply for this role.

The Molecular Genetics department at the Allen Institute for Brain Science seeks to hire an exceptional individual who will lead methods development for single-cell/nucleus genomics methods (RNA-seq, ATAC-seq, multimodal approaches) using cells/nuclei isolated from adult, developing and aged mouse brain.

Essential Duties

  • Design, test and optimize methods for single cell genomics including ones described above.
  • Collaborate with Bioinformatics scientists to analyze and interpret the data.
  • Guide introduction of techniques into the existing Allen Institute pipelines.
  • Work across teams to test new genomics approaches cross-species.
  • Present work internally and externally at conferences.

Required Education and Experience

  • Bachelor's in Neuroscience, Cell Biology, Molecular Biology or a related life science discipline with at least 4 years’ experience post bachelor's degree
  • Extensive experience with single cell genomics methods, experimental development and troubleshooting.
  • Strong molecular biology skills; PCR, RT-PCR, mRNA and DNA prep.
  • Familiarity with mouse brain anatomy.

Preferred Education and Experience

  • Bachelor's of Science in Neuroscience, Cell Biology, Molecular Biology or a related life science discipline.
  • Positive attitude, self-motivated, and ability to troubleshoot.
  • Exceptional oral and written communication skills.
  • Proficiency in R and/or python and linux shell scripting.
  • Knowledgeable about mouse genetics.
  • Ability to work independently and within a collaborative, multi-disciplinary environment to meet aggressive timelines.

Work Environment

  • Frequently required to sit, stand, walk, stoop, kneel or reach
  • Exposure and handling of laboratory animals required
  • Laboratory atmosphere - possible exposure to chemical, biological or other hazardous substances

Physical Demands

  • Occasional lifting to 30 pounds
  • Fine motor movements in fingers/hands to operate computers and other office equipment; lab equipment

Position Type

  • This is an onsite, M-F, regular business hours position. During the time of COVID we are constantly reviewing our onsite requirements. 

It is the policy of the Allen Institute to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by federal, state or local law. In addition, the Allen Institute will provide reasonable accommodations for qualified individuals with disabilities.

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