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Associate Director, Imaging in Brain Science

Department: 3480 - Imaging
Location: Seattle

Associate Director, Imaging

Our mission at the Allen Institute for Brain Science is to accelerate the understanding of how the human brain works in health and disease. Using a big science approach, we generate useful public resources, drive technological and analytical advances, and discover fundamental brain properties through integration of experiments, modeling and theory.

The Allen Institute believes that team science significantly benefits from the participation of diverse voices, experiences and backgrounds. High-quality science can only be produced when it includes different perspectives. We are committed to increasing diversity across every team and encourage people from all backgrounds to apply for this role.

We are seeking a neuroscientist with strong expertise and experience in microscopy to oversee a team in providing a variety of imaging services, as well as developing new imaging capabilities, for Allen Institute’s large-scale research and production projects. The associate director will work under the big science and team science principle, facilitating close coordination and collaboration with other institute teams towards achieving our goal of understanding the cell type composition and function of cortical circuits. This position is equivalent to an Associate Investigator or Associate Professor role.

Essential Functions:

  • Lead a team of technical and scientific staff on experimental design, technology development and implementation, assay execution and routine imaging activities required for various scientific projects.
  • Accountable for the achievement of strategic outcomes and the generation of high-quality datasets.
  • Develop annual objectives within the scope of the strategic plan and assuring integration with other teams and external partners.
  • Manage and maintain our high-throughput core imaging facilities, including bright-field, epifluorescence, confocal and 2-photon microscopy.
  • Work with scientists and engineers to develop and/or incorporate new large-scale imaging capabilities to systematically investigate gene expression and neuronal morphology/connectivity in brain tissues.
  • Lead and collaborate with other scientific and management teams in data generation and analysis of pipeline and/or small research projects, grant applications and publications.
  • Regularly present data (in oral and/or written form) to the internal and external research communities.
  • Work with internal teams and external partners to facilitate data organization, integration and dissemination through web-based resources and tools
  • Other duties as assigned.

Required Education and Experience:

  • Doctoral degree (Ph.D. or M.D.) in neuroscience, biology, physics, or other related field, plus 6+ years of post-graduate relevant experience.
  • Strong technical expertise in microscopy.
  • Prior experience managing technical and scientific staff in a research setting.
  • Excellent organizational, written and verbal communication skills, and interpersonal skills.
  • Strong desire and motivation to contribute to Big Science, Team Science projects.

Preferred Education and Experience:

  • Experience working in a cross disciplinary environment in academia or industry, experience working in a high throughput facility is preferred.
  • Track record of implementing and improving processes and structures in a research setting.
  • Excellent collaboration skills, and ability to manage projects as well as people at multiple levels of the organization.
  • In-depth knowledge and broad understanding of microscopy and its applications to neuroscience at the cellular and circuit level, including high resolution imaging for three-dimensional neuronal morphology and reconstruction as well as circuit tracing using virus-based techniques.
  • Experience with spatial transcriptomics utilizing in situ fluorescence microscopy techniques and microscopes with advanced fluidics systems for on-rig specimen manipulation.
  • Familiarity with advanced techniques such as Light Sheet microscopy, mesoSPIM, and/or related techniques.
  • Familiarity with related software for large scale data management and analysis.
  • Experience with composition and submission of NIH grant applications

Work Environment

  • Frequently required to sit, stand, walk, stoop, kneel or reach
  • Exposure and handling of laboratory animals
  • Laboratory atmosphere - possible exposure to chemical, biological or other hazardous substances

Physical Demands

  • Occasional lifting to 30 pounds
  • Fine motor movements in fingers/hands to operate computers and other office equipment; lab equipment

Position Type/Expected Hours of Work

  • This role is currently working onsite and remotely due to COVID-19 and our focus on employee safety. We continue to evaluate the safest options for our employees.

It is the policy of the Allen Institute to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by federal, state or local law. In addition, the Allen Institute will provide reasonable accommodations for qualified individuals with disabilities.

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