Scientist I – Neuromodulation and Neural Circuit Computation – Neural Dynamics

The mission of the Allen Institute is to unlock the complexities of bioscience and advance our knowledge to improve human health. Using an open science, multi-scale, team-oriented approach, the Allen Institute focuses on accelerating foundational research, developing standards and models, and cultivating new ideas to make a broad, transformational impact on science.

The Allen Institute for Neural Dynamics is focused on making fundamental discoveries in systems neuroscience. We are interested in how the brain builds our understanding of the complex world to guide the flexible behaviors. The answers will be in terms of defined neuron types and circuits. Employing a team-based approach for discovery neuroscience, we strive to uncover the neural basis of behavior through technological innovation, cutting-edge experiments, modeling, and theory.

We are seeking a scientist to lead a project to uncover the functions of neuromodulators (e.g., serotonin, norepinephrine, dopamine) and their impact on downstream networks across the mouse brain, with an emphasis on neural circuit computation. Experiments will include measurements and manipulations of neurotransmitter release, neuronal activity, and behavior. The ideal candidate will be team-oriented, with expertise in electrophysiology, optical physiology, and neural computations in brain-wide circuits. This position will leverage state-of-the-art behavioral, computational, electrophysiological, and imaging methods, as well as molecular and transgenic resources.

At the Allen Institute, we believe that science is for everyone – and should be open to everyone. We are dedicated to combating biases and reducing barriers to STEM careers more broadly. We also believe that science is better when it includes different perspectives and voices. We strive to make the Allen Institute a place where everyone feels like they belong and are empowered to do their best work in a supportive environment.

We are an equal-opportunity employer and strongly encourage people from all backgrounds to apply for our open positions.

Essential Functions

• Design and perform experiments involving in vivo electrophysiology, optical physiology, and mouse behavior
• Develop and implement quantitative models and analyses of behavior and neural measurements
• Collaborate with scientists and engineers to develop and evaluate methods for data collection, quantification, and analysis
• Train team members to perform procedures
• Collaborate internally and externally to analyze data and develop hypotheses
• Present results internally, via talks and progress reports, and to the external community, via conferences and publications

Note: Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. This description reflects management’s assignment of essential functions; it does not proscribe or restrict the tasks that may be assigned.

Required Education and Experience

• PhD in neuroscience, biological sciences, biomedical engineering, or related field; or equivalent combination of degree and experience

Preferred Education and Experience

• 0-5 years of postdoctoral experience
• Experience with neurophysiology and behavior
• Demonstrated proficiency in conducting collaborative, multidisciplinary research
• Strong understanding of statistics and data science
• Ability to write reusable code in Python
• Excellent written and verbal communication skills
• Strong publication record

Work Environment

• May enter laboratory environment, including potential exposure to lasers, biohazards

Physical Demands

• Fine motor movements in fingers/hands to operate computers and other office equipment; repetitive motion with lab equipment
• Stooping, bending, crouching
• Reaching, or climbing ladders

Position Type/Expected Hours of Work

• This role is currently working onsite and is expected to work onsite for the majority of working hours. The primary work location for this role is 615 Westlake Ave N., with flexibility to work remotely on a limited basis. We are a Washington State employer; any remote work must be performed in Washington State.

Travel

• Occasional participation in national and international conferences required

Additional Comments

• **Please note, this opportunity offers relocation assistance**
• **Please note, this opportunity offers work visa sponsorship**

Annualized Salary Range

• $84,900 - $105,050

* Final salary depends on required education for the role, experience, and level of skills relevant to the role, along with work location, where applicable.

Benefits

• Employees (and their families) are eligible to enroll in benefits per eligibility rules outlined in the Allen Institute’s Benefits Guide. These benefits include medical, dental, vision, and basic life insurance. Employees are also eligible to enroll in the Allen Institute’s 401k plan. Paid time off is also available as outlined in the Allen Institute's Benefits Guide. Details on the Allen Institute’s benefits offering are located at the following link to the Benefits Guide: https://alleninstitute.org/careers/benefits.

It is the policy of the Allen Institute to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status about public assistance, veteran status, or any other characteristic protected by federal, state or local law. In addition, the Allen Institute will provide reasonable accommodations for qualified individuals with disabilities.